WebSide effects due to simvastatin-containing medications should be reported to the FDA MedWatch program. 7. Managing simvastatin therapy. Simvastatin doses should be titrated appropriately to a maximum of 40 mg. If LDL-cholesterol goals cannot be achieved with simvastatin 20-40 mg, the patient should be switched to a more potent statin, WebJan 12, 2024 · Sequestrants. Another alternative to statins is bile acid-binding resins, or sequestrants. These drugs work by binding to the bile in your intestines and thereby blocking cholesterol absorption ...
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WebDec 11, 2014 · The following statin side effect incidences have been estimated based on randomised trial data, cohort studies, published case reports and spontaneous reports: … WebUncommon side effects of statins include: being sick. memory problems. hair loss. pins and needles. inflammation of the liver (hepatitis), which can cause flu-like symptoms. … smgb plenty valley
Considerations for Safe Use of Statins: Liver Enzyme ... - AAFP
WebSeveral factors may increase the likelihood of statin-induced myopathy . 16 Multiple clinical trials have found that the risk of myopathy is dose-dependent, especially with simvastatin. 17, 19 The ... WebDec 31, 2024 · The most effective statin drug is rosuvastatin with a 40 mg dose lowering LDL-C (the bad cholesterol) by 55%. It also raised the good HDL cholesterol by 10% and lowered triglycerides by 28%. Simvastatin and pravastatin hold the distinguished designation of being the most tolerable statins with the fewest side effects. WebAlthough generally well tolerated, statin users frequently report muscle-related side effects, ranging from self-limiting myalgias to rhabdomyolysis or the rare entity of statin-associated immune-mediated necrotizing myopathy (IMNM). 4 Based on recently published guidelines for the management of cholesterol by the American College of Cardiology and the … smgb playford