Nettet25. mai 2024 · Chronic kidney disease (CKD) affects over 10% of the worldwide population and kidney fibrosis is a main driver of CKD and considered a therapeutic target. The mechanisms leading to kidney fibrosis are highly complexed and can be best studied in rodent models. Here we... NettetAs the genetic basis of human kidney disease continues to unfold, new mouse models will undoubtedly become available that could serve as additional experimental CKD models. Current challenges include the need for models with practical time courses – early death (as occurs in the nephrin−/− mice [ 38 ]), or disease that develops over long periods of …
Mouse Models of Kidney Fibrosis Springer Nature Experiments
Nettet7. feb. 2024 · To date, good experimental mouse models of renal anemia are not available. Here, we have established stable renal anemia in mice. We showed that … Nettet30. jun. 2013 · On the contrary, other studies have reported platelet hyperactivity and increased thrombogenicity in a rat or mouse model of CKD induced by 5/6 ablation/infarction [10, 11]. stephen hawking children\u0027s books
Developing better mouse models to study cisplatin-induced …
NettetNational Center for Biotechnology Information NettetClarifying the relationship between periodontitis, AS and CKD is of great significance to further explore the overall relationship between periodontitis, AS and CKD. In this study, we established a mouse model of periodontitis and/or AS, evaluated the expression of renal inflammatory markers, and analyzed the changes of serum renal function ... NettetExogenous erythropoietin (EPO) is used to treat anemia in patients with chronic kidney disease (CKD). Concerns about the possible adverse effect of EPO on the progression of CKD have been raised owing to nonerythroid cell effects. We investigated the effects of low-dose EPO, independent of correctin … pioneer sx-s30 中古