WebAug 26, 2024 · We used proteomic analysis to compare the protein expression within (1) a parental triple negative human breast cancer cell line, (2) a fully bone homing cell line and (3) a lung homing cell line. ... Proteomics identified Dedicator of Cytokinesis 4 as a biomarker predictive of bone spread, and this finding was further supported by the ... WebDedicator of cytokinesis 8-deficient CD4 + T cells are biased to a T H 2 effector fate at the expense of T H 1 and T H 17 cells J Allergy Clin Immunol. 2024 Mar;139(3):933-949. doi: 10.1016/j.jaci.2016.07.016. Epub 2016 Aug 20. Authors Stuart G Tangye 1 ... DOCK8 protein, human
Circular forms of dedicator of cytokinesis 1 promotes breast …
WebJan 9, 2007 · Protein Dedicator of cytokinesis protein 7 Gene DOCK7 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 2140 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Align Download Add Add a publication Entry feedback … WebDec 29, 2011 · Dedicator of cytokinesis 1 (Dock1 or Dock180) is a guanine nucleotide exchange factor (GEF) that activates Rac1 and controls several cellular functions, including cell motility, survival, and proliferation ().Dock180 facilitates nucleotide exchange on Rac1 through its Dock-homology region-2 (DHR-2) domain, but requires binding to engulfment … upchurch cincinnati
DOCK1 Gene - GeneCards DOCK1 Protein DOCK1 Antibody
Webdedicator of cytokinesis 8 Normal Function Collapse Section The DOCK8 gene provides instructions for making a member of the DOCK family of proteins. The proteins in this family act as guanine nucleotide exchange factors (GEFs). GEFs turn on (activate) proteins called GTPases, which play an important role in chemical signaling within cells. WebNov 15, 2024 · DEDICATOR OF CYTOKINESIS 11; DOCK11 Alternative titles; symbols ACTIVATED CDC42-ASSOCIATED GUANINE NUCLEOTIDE EXCHANGE FACTOR; ACG ZIZIMIN 2; ZIZ2 HGNC Approved Gene Symbol: DOCK11 Cytogenetic location: Xq24 Genomic coordinates (GRCh38): X:118,495,815-118,686,147 (from NCBI) TEXT Cloning … WebDedicator of cytokinesis protein 7 Gene Dock7 Status UniProtKB unreviewed (TrEMBL) Organism Mus musculus (Mouse) Amino acids 2128 Protein existence Evidence at protein level Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function GO annotations Expand table upchurch cds 2022