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WebSep 19, 2024 · Long-term findings from the phase III, CheckMate 238 study showed that nivolumab improved 4-year recurrence-free survival (RFS) compared with ipilimumab in patients with resected stage IIIB-C or IV melanoma in the overall population and across subgroups of patients stratified by disease stage (per AJCC 7th edition) and tumour … of these findings. The phase III CheckMate 8Y8 trial (ClinicalTrials.gov identifier: NCT03873402)is comparing nivolumab with ipilimumab/nivolumab in untreated patients. The phase III PEDIGREE23 study (ClinicalTrials.gov identifier: NCT03793166)aimsto enroll . 1,000 patients for up-front ipilimumab/ nivolumab with response-adaptive mechanism ... hawkins hayle reviews
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