Buforin2
Web(A) A schematic of BR2 containing PR-PPD peptides. Polyproline domain (PPD) of human progesterone receptor (PR) was added to the C-terminal of the cell-penetrating peptide (CPP), Buforin2 (BR2). The nucleotide sequences were cloned into a pPICZαA expression vector and transformed into Pichia pastoris KM71H by electroporation. All peptides were ... WebJun 25, 2013 · In conclusion, we have successfully generated a pSUR-Buforin2 recombinant plasmid that can achieve selective cytotoxicity in tumor cells by activating apoptotic pathways and inhibiting cell proliferation. Our study suggests that the pSUR-Buforin2 plasmid should be further investigated for its use in treating cancer.
Buforin2
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WebKeygen Biotech human normal liver cell lo2 Human Normal Liver Cell Lo2, supplied by Keygen Biotech, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. WebResults: The pSUR-Buforin2 vector effectively suppressed the proliferation of HepG2 cells. The MTT and LDH assay demonstrated that under control of the survivin promoter, Buforin II was not expressed in LO2 cells, but it was expressed in tumor cells where cell death was also observed. AnnexinV-PI staining, DNA ladder assays, and western blots ...
WebJun 23, 2024 · Examples of these AMPs include buforin2 8 and indolicidin 9. The salt sensitivity of AMPs is a major limitation to the development of AMPs as treatment agents 10. AMPs interact electrostatically with the microbial membrane in a salt-sensitive manner. Web提供抗菌肽magainin对E.coli杀伤作用的AFM观察word文档在线阅读与免费下载，摘要:第25卷第1期2006年2月电 子 显 微 学 报 ...
WebMar 6, 1998 · The mechanism of action of buforin II, which is a 21-amino acid peptide with a potent antimicrobial activity against a broad range of microorganisms, was studied … WebApr 28, 2008 · Buforin II (BF2) is an antimicrobial peptide that is hypothesized to kill bacteria by entering cells and binding nucleic acids. To further investigate this proposed mechanism, we used computer modeli...
WebJul 11, 2000 · A 39-aa peptide, buforin I, was isolated from the stomach tissue of the Asian toad Bufo bufo garagrizans, and a more potent antimicrobial peptide of 21 amino acids, …
WebThe expression of PCNA in HepG2/pSUR-Buforin2 was lower than the HepG2 and HepG2/pSUR-Luc groups. Cleaved Caspase 3 levels were higher in the HepG2/pSUR-Buforin2 group than the other groups. fox river water temperature green bayWebJun 23, 2024 · Examples of these AMPs include buforin2 8 and indolicidin 9. The salt sensitivity of AMPs is a major limitation to the development of AMPs as treatment agents 10. AMPs interact electrostatically ... fox river waukesha wiWebFeb 28, 2024 · Here, we conjugated the antimicrobial CPP buforin II (BUF2) to the surface of magnetite nanoparticles to enhance their cell penetration. Conjugates were characterized via Fourier transform infrared spectroscopy, dynamic light scattering, and thermogravimetric analysis, and their biocompatibility was corroborated. black white plaid pajama pantsWebSep 16, 2013 · Abstract Objective: The aim of this study was to investigate the suppressive effects of Buforin II on the growth of HepG2 cells. To accomplish this, we created a … fox river wedding venueWebOBJECTIVE: The aim of this study was to investigate the suppressive effects of Buforin II on the growth of HepG2 cells. To accomplish this, we created a recombinant plasmid (pSUR-Buforin2) in which the survivin promoter was modified to drive the Buforin II gene. METHODS: The DNA fragment encoding the Buforin II gene was obtained by gene … black white plus size clothingfox river west coast accommodationWebDec 24, 2024 · The emergence of drug-resistant bacteria emphasizes the urgent need for novel antibiotics. The antimicrobial peptide TS shows extensive antibacterial activity in vitro and in vivo, especially in gram-negative bacteria; however, its antibacterial mechanism is unclear. Here, we find that TS without hemolytic activity disrupts the integrity of the outer … black white png